TY - JOUR AU - Hagmann, P. AU - Sporns, O. AU - Madan, N. AU - Cammoun, L. AU - Pienaar, R. AU - Wedeen, V. J. PY - 2010 DA - 2010// TI - White matter maturation reshapes structural connectivity in the late developing human brain JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.1009073107 DO - 10.1073/pnas.1009073107 ID - Hagmann2010 ER - TY - JOUR AU - Nave, K. A. AU - Werner, H. B. PY - 2014 DA - 2014// TI - Myelination of the nervous system: mechanisms and functions JO - Annu Rev Cell Dev Biol VL - 30 UR - https://doi.org/10.1146/annurev-cellbio-100913-013101 DO - 10.1146/annurev-cellbio-100913-013101 ID - Nave2014 ER - TY - JOUR AU - Franklin, R. J. AU - Edgar, J. M. AU - Smith, K. J. PY - 2012 DA - 2012// TI - Neuroprotection and repair in multiple sclerosis JO - Nat Rev Neurol VL - 8 UR - https://doi.org/10.1038/nrneurol.2012.200 DO - 10.1038/nrneurol.2012.200 ID - Franklin2012 ER - TY - JOUR AU - Court, F. A. AU - Coleman, M. P. PY - 2012 DA - 2012// TI - Mitochondria as a central sensor for axonal degenerative stimuli JO - Trends Neurosci VL - 35 UR - https://doi.org/10.1016/j.tins.2012.04.001 DO - 10.1016/j.tins.2012.04.001 ID - Court2012 ER - TY - JOUR AU - Lassmann, H. PY - 2010 DA - 2010// TI - Axonal and neuronal pathology in multiple sclerosis: what have we learnt from animal models JO - Exp Neurol VL - 225 UR - https://doi.org/10.1016/j.expneurol.2009.10.009 DO - 10.1016/j.expneurol.2009.10.009 ID - Lassmann2010 ER - TY - JOUR AU - Harris, J. J. AU - Attwell, D. PY - 2012 DA - 2012// TI - The energetics of CNS white matter JO - J Neurosci VL - 32 UR - https://doi.org/10.1523/JNEUROSCI.3430-11.2012 DO - 10.1523/JNEUROSCI.3430-11.2012 ID - Harris2012 ER - TY - JOUR AU - Conforti, L. AU - Gilley, J. AU - Coleman, M. P. PY - 2014 DA - 2014// TI - Wallerian degeneration: an emerging axon death pathway linking injury and disease JO - Nat Rev Neurosci VL - 15 UR - https://doi.org/10.1038/nrn3680 DO - 10.1038/nrn3680 ID - Conforti2014 ER - TY - JOUR AU - Adalbert, R. AU - Coleman, M. P. PY - 2013 DA - 2013// TI - Review: Axon pathology in age-related neurodegenerative disorders JO - Neuropathol Appl Neurobiol VL - 39 UR - https://doi.org/10.1111/j.1365-2990.2012.01308.x DO - 10.1111/j.1365-2990.2012.01308.x ID - Adalbert2013 ER - TY - JOUR AU - Nave, K. A. PY - 2010 DA - 2010// TI - Myelination and support of axonal integrity by glia JO - Nature VL - 468 UR - https://doi.org/10.1038/nature09614 DO - 10.1038/nature09614 ID - Nave2010 ER - TY - STD TI - Jurgens T, Jafari M, Kreutzfeldt M, Bahn E, Bruck W, Kerschensteiner M, et al. Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis. Brain. 2015.;139(Pt 1):39–46 ID - ref10 ER - TY - JOUR AU - Lipton, S. A. PY - 2007 DA - 2007// TI - Pathologically activated therapeutics for neuroprotection JO - Nat Rev Neurosci VL - 8 UR - https://doi.org/10.1038/nrn2229 DO - 10.1038/nrn2229 ID - Lipton2007 ER - TY - JOUR AU - Giunti, D. AU - Parodi, B. AU - Cordano, C. AU - Uccelli, A. AU - Kerlero de Rosbo, N. PY - 2014 DA - 2014// TI - Can we switch microglia's phenotype to foster neuroprotection? Focus on multiple sclerosis JO - Immunology VL - 141 UR - https://doi.org/10.1111/imm.12177 DO - 10.1111/imm.12177 ID - Giunti2014 ER - TY - JOUR AU - Colombo, E. AU - Dario, M. AU - Capitolo, E. AU - Chaabane, L. AU - Newcombe, J. AU - Martino, G. PY - 2014 DA - 2014// TI - Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide JO - Ann Neurol VL - 76 UR - https://doi.org/10.1002/ana.24217 DO - 10.1002/ana.24217 ID - Colombo2014 ER - TY - JOUR AU - Reick, C. AU - Ellrichmann, G. AU - Thone, J. AU - Scannevin, R. H. AU - Saft, C. AU - Linker, R. A. PY - 2014 DA - 2014// TI - Neuroprotective dimethyl fumarate synergizes with immunomodulatory interferon beta to provide enhanced axon protection in autoimmune neuroinflammation JO - Exp Neurol VL - 257 UR - https://doi.org/10.1016/j.expneurol.2014.04.003 DO - 10.1016/j.expneurol.2014.04.003 ID - Reick2014 ER - TY - JOUR AU - Ruffini, F. AU - Rossi, S. AU - Bergamaschi, A. AU - Brambilla, E. AU - Finardi, A. AU - Motta, C. PY - 2013 DA - 2013// TI - Laquinimod prevents inflammation-induced synaptic alterations occurring in experimental autoimmune encephalomyelitis JO - Mult Scler VL - 19 UR - https://doi.org/10.1177/1352458512469698 DO - 10.1177/1352458512469698 ID - Ruffini2013 ER - TY - JOUR AU - Aharoni, R. PY - 2014 DA - 2014// TI - Immunomodulation neuroprotection and remyelination - the fundamental therapeutic effects of glatiramer acetate: a critical review JO - J Autoimmun VL - 54 UR - https://doi.org/10.1016/j.jaut.2014.05.005 DO - 10.1016/j.jaut.2014.05.005 ID - Aharoni2014 ER - TY - JOUR AU - Loeb, J. A. PY - 2007 DA - 2007// TI - Neuroprotection and repair by neurotrophic and gliotrophic factors in multiple sclerosis JO - Neurology VL - 68 UR - https://doi.org/10.1212/01.wnl.0000275231.97764.43 DO - 10.1212/01.wnl.0000275231.97764.43 ID - Loeb2007 ER - TY - JOUR AU - Villoslada, P. AU - Genain, C. P. PY - 2004 DA - 2004// TI - Role of nerve growth factor and other trophic factors in brain inflammation JO - Prog Brain Res VL - 146 UR - https://doi.org/10.1016/S0079-6123(03)46025-1 DO - 10.1016/S0079-6123(03)46025-1 ID - Villoslada2004 ER - TY - JOUR AU - Segal, R. A. PY - 2003 DA - 2003// TI - Selectivity in neurotrophin signaling: theme and variations JO - Annu Rev Neurosci VL - 26 UR - https://doi.org/10.1146/annurev.neuro.26.041002.131421 DO - 10.1146/annurev.neuro.26.041002.131421 ID - Segal2003 ER - TY - JOUR AU - Villoslada, P. AU - Hauser, S. L. AU - Bartke, I. AU - Unger, J. AU - Heald, N. AU - Rosenberg, D. PY - 2000 DA - 2000// TI - Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the central nervous system JO - J Exp Med VL - 191 UR - https://doi.org/10.1084/jem.191.10.1799 DO - 10.1084/jem.191.10.1799 ID - Villoslada2000 ER - TY - JOUR AU - Colafrancesco, V. AU - Villoslada, P. PY - 2011 DA - 2011// TI - Targeting NGF pathway for developing neuroprotective therapies for multiple sclerosis and other neurological diseases JO - Arch Ital Biol VL - 149 ID - Colafrancesco2011 ER - TY - STD TI - The BDNF Study Group (Phase III). A controlled trial of recombinant methionyl human BDNF in ALS: Neurology. 1999;52(7):1427–33. ID - ref22 ER - TY - STD TI - ALS CNTF Treatment Study Group. A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. Neurology. 1996;46(5):1244–9. ID - ref23 ER - TY - JOUR AU - Sorenson, E. J. AU - Windbank, A. J. AU - Mandrekar, J. N. AU - Bamlet, W. R. AU - Appel, S. H. AU - Armon, C. PY - 2008 DA - 2008// TI - Subcutaneous IGF-1 is not beneficial in 2-year ALS trial JO - Neurology VL - 71 UR - https://doi.org/10.1212/01.wnl.0000335970.78664.36 DO - 10.1212/01.wnl.0000335970.78664.36 ID - Sorenson2008 ER - TY - JOUR AU - Tuszynski, M. H. AU - Thal, L. AU - Pay, M. AU - Salmon, D. P. AU - Bakay, R. PY - 2005 DA - 2005// TI - A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease JO - Nat Med VL - 11 UR - https://doi.org/10.1038/nm1239 DO - 10.1038/nm1239 ID - Tuszynski2005 ER - TY - JOUR AU - Cudkowicz, M. E. AU - Katz, J. AU - Moore, D. H. AU - O'Neill, G. AU - Glass, J. D. AU - Mitsumoto, H. PY - 2010 DA - 2010// TI - Toward more efficient clinical trials for amyotrophic lateral sclerosis JO - Amyotroph Lateral Scler VL - 11 UR - https://doi.org/10.3109/17482960903358865 DO - 10.3109/17482960903358865 ID - Cudkowicz2010 ER - TY - JOUR AU - Apfel, S. C. PY - 2002 DA - 2002// TI - Nerve growth factor for the treatment of diabetic neuropathy: what went wrong, what went right, and what does the future hold? JO - Int Rev Neurobiol VL - 50 UR - https://doi.org/10.1016/S0074-7742(02)50083-0 DO - 10.1016/S0074-7742(02)50083-0 ID - Apfel2002 ER - TY - JOUR AU - Beal, M. F. PY - 2005 DA - 2005// TI - Mitochondria take center stage in aging and neurodegeneration JO - Ann Neurol VL - 58 UR - https://doi.org/10.1002/ana.20624 DO - 10.1002/ana.20624 ID - Beal2005 ER - TY - JOUR AU - Schapira, A. H. AU - Olanow, C. W. AU - Greenamyre, J. T. AU - Bezard, E. PY - 2014 DA - 2014// TI - Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives JO - Lancet VL - 384 UR - https://doi.org/10.1016/S0140-6736(14)61010-2 DO - 10.1016/S0140-6736(14)61010-2 ID - Schapira2014 ER - TY - JOUR AU - Tiwari, S. K. AU - Chaturvedi, R. K. PY - 2014 DA - 2014// TI - Peptide therapeutics in neurodegenerative disorders JO - Curr Med Chem VL - 21 UR - https://doi.org/10.2174/0929867321666140217125857 DO - 10.2174/0929867321666140217125857 ID - Tiwari2014 ER - TY - JOUR AU - Ries, V. AU - Oertel, W. H. AU - Hoglinger, G. U. PY - 2011 DA - 2011// TI - Mitochondrial dysfunction as a therapeutic target in progressive supranuclear palsy JO - J Mol Neurosci VL - 45 UR - https://doi.org/10.1007/s12031-011-9606-3 DO - 10.1007/s12031-011-9606-3 ID - Ries2011 ER - TY - STD TI - Errea O, B M, Gonzalez-Franquesa A, Garcia-Roves P, Villoslada P. The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation. 2015;12:152–167. ID - ref32 ER - TY - JOUR AU - Waxman, S. G. PY - 2006 DA - 2006// TI - Axonal conduction and injury in multiple sclerosis: the role of sodium channels JO - Nat Rev Neurosci VL - 7 UR - https://doi.org/10.1038/nrn2023 DO - 10.1038/nrn2023 ID - Waxman2006 ER - TY - JOUR AU - Waxman, S. G. PY - 2008 DA - 2008// TI - Mechanisms of disease: sodium channels and neuroprotection in multiple sclerosis-current status JO - Nat Clin Pract Neurol VL - 4 UR - https://doi.org/10.1038/ncpneuro0735 DO - 10.1038/ncpneuro0735 ID - Waxman2008 ER - TY - JOUR AU - Sureda, F. X. AU - Junyent, F. AU - Verdaguer, E. AU - Auladell, C. AU - Pelegri, C. AU - Vilaplana, J. PY - 2011 DA - 2011// TI - Antiapoptotic drugs: a therapautic strategy for the prevention of neurodegenerative diseases JO - Curr Pharm Des VL - 17 UR - https://doi.org/10.2174/138161211795049732 DO - 10.2174/138161211795049732 ID - Sureda2011 ER - TY - JOUR AU - Lassmann, H. PY - 2014 DA - 2014// TI - Multiple sclerosis: Lessons from molecular neuropathology JO - Exp Neurol VL - 262PA UR - https://doi.org/10.1016/j.expneurol.2013.12.003 DO - 10.1016/j.expneurol.2013.12.003 ID - Lassmann2014 ER - TY - JOUR AU - Haider, L. AU - Fischer, M. T. AU - Frischer, J. M. AU - Bauer, J. AU - Hoftberger, R. AU - Botond, G. PY - 2011 DA - 2011// TI - Oxidative damage in multiple sclerosis lesions JO - Brain VL - 134 UR - https://doi.org/10.1093/brain/awr128 DO - 10.1093/brain/awr128 ID - Haider2011 ER - TY - STD TI - Niedzielska E, Smaga I, Gawlik M, Moniczewski A, Stankowicz P, Pera J, et al. Oxidative Stress in Neurodegenerative Diseases. Mol Neurobiol. 2015. in press. ID - ref38 ER - TY - JOUR AU - Linker, R. A. AU - Lee, D. H. AU - Ryan, S. AU - Dam, A. M. AU - Conrad, R. AU - Bista, P. PY - 2011 DA - 2011// TI - Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway JO - Brain VL - 134 UR - https://doi.org/10.1093/brain/awq386 DO - 10.1093/brain/awq386 ID - Linker2011 ER - TY - JOUR AU - Lanza, C. AU - Morando, S. AU - Voci, A. AU - Canesi, L. AU - Principato, M. C. AU - Serpero, L. D. PY - 2009 DA - 2009// TI - Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effect in vivo JO - J Neurochem VL - 110 UR - https://doi.org/10.1111/j.1471-4159.2009.06268.x DO - 10.1111/j.1471-4159.2009.06268.x ID - Lanza2009 ER - TY - JOUR AU - Fern, R. F. AU - Matute, C. AU - Stys, P. K. PY - 2014 DA - 2014// TI - White matter injury: Ischemic and nonischemic JO - Glia VL - 62 UR - https://doi.org/10.1002/glia.22722 DO - 10.1002/glia.22722 ID - Fern2014 ER - TY - JOUR AU - Kostic, M. AU - Zivkovic, N. AU - Stojanovic, I. PY - 2013 DA - 2013// TI - Multiple sclerosis and glutamate excitotoxicity JO - Rev Neurosci VL - 24 UR - https://doi.org/10.1515/revneuro-2012-0062 DO - 10.1515/revneuro-2012-0062 ID - Kostic2013 ER - TY - JOUR AU - Mitsumoto, H. PY - 1997 DA - 1997// TI - Riluzole--what is its impact in our treatment and understanding of amyotrophic lateral sclerosis? JO - Ann Pharmacother VL - 31 ID - Mitsumoto1997 ER - TY - STD TI - Lipton SA. Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond. Nat Rev Drug Discov. 2006;1–11. ID - ref44 ER - TY - JOUR AU - Villoslada, P. AU - Arrondo, G. AU - Sepulcre, J. AU - Alegre, M. AU - Artieda, J. PY - 2008 DA - 2008// TI - Memantine induces reversible neurologic impairment in patients with MS JO - Neurology VL - 72 UR - https://doi.org/10.1212/01.wnl.0000342388.73185.80 DO - 10.1212/01.wnl.0000342388.73185.80 ID - Villoslada2008 ER - TY - JOUR AU - Green, A. J. PY - 2009 DA - 2009// TI - Understanding pseudo: the symptoms are real, the cause is unclear JO - Neurology VL - 72 UR - https://doi.org/10.1212/01.wnl.0000345879.39454.68 DO - 10.1212/01.wnl.0000345879.39454.68 ID - Green2009 ER - TY - JOUR AU - Nave, K. A. AU - Trapp, B. D. PY - 2008 DA - 2008// TI - Axon-glial signaling and the glial support of axon function JO - Annu Rev Neurosci VL - 31 UR - https://doi.org/10.1146/annurev.neuro.30.051606.094309 DO - 10.1146/annurev.neuro.30.051606.094309 ID - Nave2008 ER - TY - JOUR AU - DeLuca, G. C. AU - Williams, K. AU - Evangelou, N. AU - Ebers, G. C. AU - Esiri, M. M. PY - 2006 DA - 2006// TI - The contribution of demyelination to axonal loss in multiple sclerosis JO - Brain VL - 129 UR - https://doi.org/10.1093/brain/awl074 DO - 10.1093/brain/awl074 ID - DeLuca2006 ER - TY - JOUR AU - Elskamp, I. J. AU - Knol, D. L. AU - Vrenken, H. AU - Karas, G. AU - Meijerman, A. AU - Filippi, M. PY - 2010 DA - 2010// TI - Lesional magnetization transfer ratio: a feasible outcome for remyelinating treatment trials in multiple sclerosis JO - Mult Scler VL - 16 UR - https://doi.org/10.1177/1352458510364630 DO - 10.1177/1352458510364630 ID - Elskamp2010 ER - TY - JOUR AU - Vos, K. J. AU - Grierson, A. J. AU - Ackerley, S. AU - Miller, C. C. PY - 2008 DA - 2008// TI - Role of axonal transport in neurodegenerative diseases JO - Annu Rev Neurosci VL - 31 UR - https://doi.org/10.1146/annurev.neuro.31.061307.090711 DO - 10.1146/annurev.neuro.31.061307.090711 ID - Vos2008 ER - TY - JOUR AU - Sorbara, C. D. AU - Wagner, N. E. AU - Ladwig, A. AU - Nikic, I. AU - Merkler, D. AU - Kleele, T. PY - 2014 DA - 2014// TI - Pervasive axonal transport deficits in multiple sclerosis models JO - Neuron VL - 84 UR - https://doi.org/10.1016/j.neuron.2014.11.006 DO - 10.1016/j.neuron.2014.11.006 ID - Sorbara2014 ER - TY - JOUR AU - Ruschel, J. AU - Hellal, F. AU - Flynn, K. C. AU - Dupraz, S. AU - Elliott, D. A. AU - Tedeschi, A. PY - 2015 DA - 2015// TI - Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injury JO - Science VL - 348 UR - https://doi.org/10.1126/science.aaa2958 DO - 10.1126/science.aaa2958 ID - Ruschel2015 ER - TY - JOUR AU - Kim, S. AU - Chang, R. AU - Teunissen, C. AU - Gebremichael, Y. AU - Petzold, A. PY - 2011 DA - 2011// TI - Neurofilament stoichiometry simulations during neurodegeneration suggest a remarkable self-sufficient and stable in vivo protein structure JO - J Neurol Sci VL - 307 UR - https://doi.org/10.1016/j.jns.2011.04.023 DO - 10.1016/j.jns.2011.04.023 ID - Kim2011 ER - TY - JOUR AU - Llorens, F. AU - Gil, V. AU - Rio, J. A. PY - 2011 DA - 2011// TI - Emerging functions of myelin-associated proteins during development, neuronal plasticity, and neurodegeneration JO - FASEB J VL - 25 UR - https://doi.org/10.1096/fj.10-162792 DO - 10.1096/fj.10-162792 ID - Llorens2011 ER - TY - JOUR AU - Rottlaender, A. AU - Kuerten, S. PY - 2015 DA - 2015// TI - Stepchild or Prodigy? Neuroprotection in Multiple Sclerosis (MS) Research JO - Int J Mol Sci VL - 16 UR - https://doi.org/10.3390/ijms160714850 DO - 10.3390/ijms160714850 ID - Rottlaender2015 ER - TY - JOUR AU - Hernangomez, M. AU - Mestre, L. AU - Correa, F. G. AU - Loria, F. AU - Mecha, M. AU - Inigo, P. M. PY - 2012 DA - 2012// TI - CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation JO - Glia VL - 60 UR - https://doi.org/10.1002/glia.22366 DO - 10.1002/glia.22366 ID - Hernangomez2012 ER - TY - STD TI - Vecino E, Rodriguez FD, Ruzafa N, Pereiro X, Sharma SC. Glia-neuron interactions in the mammalian retina. Prog Retin Eye Res. 2015;51:1–40. ID - ref57 ER - TY - JOUR AU - Ransohoff, R. M. AU - Hafler, D. A. AU - Lucchinetti, C. F. PY - 2015 DA - 2015// TI - Multiple sclerosis-a quiet revolution JO - Nat Rev Neurol VL - 11 UR - https://doi.org/10.1038/nrneurol.2015.14 DO - 10.1038/nrneurol.2015.14 ID - Ransohoff2015 ER - TY - JOUR AU - Mahad, D. H. AU - Trapp, B. D. AU - Lassmann, H. PY - 2015 DA - 2015// TI - Pathological mechanisms in progressive multiple sclerosis JO - Lancet Neurol VL - 14 UR - https://doi.org/10.1016/S1474-4422(14)70256-X DO - 10.1016/S1474-4422(14)70256-X ID - Mahad2015 ER - TY - JOUR AU - Lassmann, H. PY - 2013 DA - 2013// TI - Pathology and disease mechanisms in different stages of multiple sclerosis JO - J Neurol Sci VL - 333 UR - https://doi.org/10.1016/j.jns.2013.05.010 DO - 10.1016/j.jns.2013.05.010 ID - Lassmann2013 ER - TY - JOUR AU - Piaton, G. AU - Gould, R. M. AU - Lubetzki, C. PY - 2010 DA - 2010// TI - Axon-oligodendrocyte interactions during developmental myelination, demyelination and repair JO - J Neurochem VL - 114 ID - Piaton2010 ER - TY - JOUR AU - Mullard, A. PY - 2011 DA - 2011// TI - Success of immunomodulators in MS shifts discovery focus to neuroprotection JO - Nat Rev Drug Discov VL - 10 UR - https://doi.org/10.1038/nrd3610 DO - 10.1038/nrd3610 ID - Mullard2011 ER - TY - JOUR AU - Weinshenker, B. G. AU - Barron, G. AU - Behne, J. M. AU - Bennett, J. L. AU - Chin, P. S. AU - Cree, B. A. PY - 2015 DA - 2015// TI - Challenges and opportunities in designing clinical trials for neuromyelitis optica JO - Neurology VL - 84 UR - https://doi.org/10.1212/WNL.0000000000001520 DO - 10.1212/WNL.0000000000001520 ID - Weinshenker2015 ER - TY - STD TI - Pittock SJ, Lucchinetti CF. Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin-4 channelopathies: a decade later. Ann N Y Acad Sci. 2015.in press. ID - ref64 ER - TY - JOUR AU - Maghzi, A. H. AU - Minagar, A. AU - Waubant, E. PY - 2013 DA - 2013// TI - Neuroprotection in multiple sclerosis: a therapeutic approach JO - CNS Drugs VL - 27 UR - https://doi.org/10.1007/s40263-013-0093-7 DO - 10.1007/s40263-013-0093-7 ID - Maghzi2013 ER - TY - JOUR AU - Aktas, O. AU - Kieseier, B. AU - Hartung, H. P. PY - 2010 DA - 2010// TI - Neuroprotection, regeneration and immunomodulation: broadening the therapeutic repertoire in multiple sclerosis JO - Trends Neurosci VL - 33 UR - https://doi.org/10.1016/j.tins.2009.12.002 DO - 10.1016/j.tins.2009.12.002 ID - Aktas2010 ER - TY - JOUR AU - Luessi, F. AU - Kuhlmann, T. AU - Zipp, F. PY - 2014 DA - 2014// TI - Remyelinating strategies in multiple sclerosis JO - Expert Rev Neurother VL - 14 UR - https://doi.org/10.1586/14737175.2014.969241 DO - 10.1586/14737175.2014.969241 ID - Luessi2014 ER - TY - JOUR AU - Mitsunaga, Y. AU - Ciric, B. AU - Keulen, V. AU - Warrington, A. E. AU - Paz Soldan, M. AU - Bieber, A. J. PY - 2002 DA - 2002// TI - Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease JO - FASEB J VL - 16 ID - Mitsunaga2002 ER - TY - JOUR AU - Mei, F. AU - Fancy, S. P. AU - Shen, Y. A. AU - Niu, J. AU - Zhao, C. AU - Presley, B. PY - 2014 DA - 2014// TI - Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis JO - Nat Med VL - 20 UR - https://doi.org/10.1038/nm.3618 DO - 10.1038/nm.3618 ID - Mei2014 ER - TY - JOUR AU - Raftopoulos, R. E. AU - Kapoor, R. PY - 2013 DA - 2013// TI - Neuroprotection for acute optic neuritis-Can it work? JO - Mult Scler Relat Disord VL - 2 UR - https://doi.org/10.1016/j.msard.2013.02.001 DO - 10.1016/j.msard.2013.02.001 ID - Raftopoulos2013 ER - TY - JOUR AU - Payne, N. AU - Siatskas, C. AU - Barnard, A. AU - Bernard, C. C. PY - 2011 DA - 2011// TI - The prospect of stem cells as multi-faceted purveyors of immune modulation, repair and regeneration in multiple sclerosis JO - Curr Stem Cell Res Ther VL - 6 UR - https://doi.org/10.2174/157488811794480735 DO - 10.2174/157488811794480735 ID - Payne2011 ER - TY - JOUR AU - Uccelli, A. AU - Moretta, L. AU - Pistoia, V. PY - 2008 DA - 2008// TI - Mesenchymal stem cells in health and disease JO - Nat Rev Immunol VL - 8 UR - https://doi.org/10.1038/nri2395 DO - 10.1038/nri2395 ID - Uccelli2008 ER - TY - JOUR AU - Llufriu, S. AU - Sepulveda, M. AU - Blanco, Y. AU - Marin, P. AU - Moreno, B. AU - Berenguer, J. PY - 2014 DA - 2014// TI - Randomized placebo-controlled phase II trial of autologous mesenchymal stem cells in multiple sclerosis JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0113936 DO - 10.1371/journal.pone.0113936 ID - Llufriu2014 ER - TY - JOUR AU - Connick, P. AU - Kolappan, M. AU - Crawley, C. AU - Webber, D. J. AU - Patani, R. AU - Michell, A. W. PY - 2012 DA - 2012// TI - Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study JO - Lancet Neurol VL - 11 UR - https://doi.org/10.1016/S1474-4422(11)70305-2 DO - 10.1016/S1474-4422(11)70305-2 ID - Connick2012 ER - TY - JOUR AU - Karussis, D. AU - Karageorgiou, C. AU - Vaknin-Dembinsky, A. AU - Gowda-Kurkalli, B. AU - Gomori, J. M. AU - Kassis, I. PY - 2010 DA - 2010// TI - Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis JO - Arch Neurol VL - 67 UR - https://doi.org/10.1001/archneurol.2010.248 DO - 10.1001/archneurol.2010.248 ID - Karussis2010 ER - TY - JOUR AU - Villoslada, P. PY - 2010 DA - 2010// TI - Biomarkers for multiple sclerosis JO - Drug News Perspect VL - 23 UR - https://doi.org/10.1358/dnp.2010.23.9.1472300 DO - 10.1358/dnp.2010.23.9.1472300 ID - Villoslada2010 ER - TY - JOUR AU - Villoslada, P. AU - Steinman, L. AU - Baranzini, S. E. PY - 2009 DA - 2009// TI - Systems biology and its application to the understanding of neurological diseases JO - Ann Neurol VL - 65 UR - https://doi.org/10.1002/ana.21634 DO - 10.1002/ana.21634 ID - Villoslada2009 ER - TY - JOUR AU - Villoslada, P. AU - Baranzini, S. PY - 2012 DA - 2012// TI - Data integration and systems biology approaches for biomarker discovery: Challenges and opportunities for multiple sclerosis JO - J Neuroimmunol VL - 248 UR - https://doi.org/10.1016/j.jneuroim.2012.01.001 DO - 10.1016/j.jneuroim.2012.01.001 ID - Villoslada2012 ER - TY - JOUR AU - Barkhof, F. AU - Calabresi, P. A. AU - Miller, D. H. AU - Reingold, S. C. PY - 2009 DA - 2009// TI - Imaging outcomes for neuroprotection and repair in multiple sclerosis trials JO - Nat Rev Neurol VL - 5 UR - https://doi.org/10.1038/nrneurol.2009.41 DO - 10.1038/nrneurol.2009.41 ID - Barkhof2009 ER - TY - JOUR AU - Martinez-Lapiscina, E. AU - Sanchez-Dalmau, B. AU - Fraga-Pumar, E. AU - Ortiz-Perez, S. AU - Tercero-Uribe, A. AU - Torres-Torres, R. PY - 2014 DA - 2014// TI - The visual pathway as a model to understand brain damage in multiple sclerosis JO - Mult Scler VL - 20 UR - https://doi.org/10.1177/1352458514542862 DO - 10.1177/1352458514542862 ID - Martinez-Lapiscina2014 ER - TY - JOUR AU - Zarbin, M. A. AU - Jampol, L. M. AU - Jager, R. D. AU - Reder, A. T. AU - Francis, G. AU - Collins, W. PY - 2013 DA - 2013// TI - Ophthalmic evaluations in clinical studies of fingolimod (FTY720) in multiple sclerosis JO - Ophthalmology VL - 120 UR - https://doi.org/10.1016/j.ophtha.2012.12.040 DO - 10.1016/j.ophtha.2012.12.040 ID - Zarbin2013 ER - TY - JOUR AU - Balcer, L. J. PY - 2014 DA - 2014// TI - Clinical trials to clinical use: using vision as a model for multiple sclerosis and beyond JO - J Neuroophthalmol VL - 34 UR - https://doi.org/10.1097/WNO.0000000000000163 DO - 10.1097/WNO.0000000000000163 ID - Balcer2014 ER - TY - JOUR AU - Sola-Valls, N. AU - Blanco, Y. AU - Sepulveda, M. AU - Llufriu, S. AU - Martinez-Lapiscina, E. H. AU - Puma, D. PY - 2015 DA - 2015// TI - Walking function in clinical monitoring of multiple sclerosis by telemedicine JO - J Neurol VL - 262 UR - https://doi.org/10.1007/s00415-015-7764-x DO - 10.1007/s00415-015-7764-x ID - Sola-Valls2015 ER -