Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Fig. 2 | Multiple Sclerosis and Demyelinating Disorders

Fig. 2

From: Increased expression of dedicator-cytokinesis-10, caspase-2 and Synaptotagmin-like 2 is associated with clinical disease activity in multiple sclerosis

Fig. 2

Validation of DEGs in a prospective cohort of patients with stable or active disease. Heat map showing the 14 DEGs validated by RT-PCR in the validation cohort: ARHGEF7, BTBD7, CASP2, CCT8, DOCK10, DSP, ITPR1, KLDHC5, PRO1073, RBBP4, SYTL2, TTC10, WDR20, ZNF75. The normalization factor was calculated using geNorm software and normalized values were transformed to a logarithmic scale. Group comparison were performed using the Kruskal-Wallis test with a significance threshold set to p < 0.01 after correction for multiple testing (Bonferoni)

Back to article page