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Table 1 Demographic and clinical features of patients with and without cognitive deficit at PML diagnosis

From: The still under-investigated role of cognitive deficits in PML diagnosis

 

Cognitive onset

No cognitive onset

 

n = 13

n = 15

Significance

Gender (♂)a

7 (53.8%)

14 (93.3%)

0.016*

Age at MS diagnosisb

25.6 (11.5)

23.3 (10.3)

0.414

Age at PML diagnosisb

39.0 (14.1)

37.5 (13.8)

0.584

MS duration (years)b

12.9 (7.3)

12.0 (9.6)

0.740

Number of infusions b

33.0 (19.5)

34.5 (20.0)

0.856

Prior Immunesoppressiona

5 (34.7%)

4 (29.4%)

0.505

Viral Loadc

324 [12–26300]

64 [11–4403]

0.271

IRIS insurgence (yes)a

11 (84.6%)

8 (53.3%)

0.077

Steroids administration (yes)a

12 (92.3%)

14 (93.3%)

0.912

Other therapies (yes)a

8 (61.5%)

10 (66.6%)

0.825

PLEX (yes)a

11 (84.6%)

8 (53.3%)

0.077

  1. Number denotes row number (a), mean (standard deviation) (b) and median [range] (c). Statistical significance was evaluated using Chi Square (a), two independent samples t test (b) and Mann Whitney test (c). *asterisk denotes statistical significance