From: The still under-investigated role of cognitive deficits in PML diagnosis
Lesion site | Cognitive deficit | Anatomo clinical correlation | How symptoms were detected | Neuropsychological tests | |
---|---|---|---|---|---|
1 | L_Parietal | Verbal memory | X | Patient’s complain + formal NPS assessment | N/A |
2 | L_Tempo Parietal | Language and reading deficits | X | Evident at neurological examination | - |
3 | L_Cerebellum | Language deficit, dementia, apraxia | - | Patient’s complain + formal NPS assessment | Mini mental state examination; Language test, apraxia test, drawing test |
4 | L_Temporal | Aphasia | X | Evident at neurological examination + formal NPS assessment | N/A |
5 | Bilateral Fronto temporo and Parietal | Spatial and temporal disorientation + perseveration + apraxia + left neglect | X | Patient’s complain + formal NPS assessment | Mini mental state examination for disorientation; Apraxia test; drawing test; Verbal fluency; Line bisection |
6 | L_Parieto occipital | Right neglect Objects’ Agnosia | X | Patient’s complain + formal NPS assessment | Line bisection; Apraxia test; Agnosia test |
7 | R_ Fronto temporal | Memory deficit Disorientation | X | Patient’s complain | - |
8 | L_Insula, ippocampus and parahippocampus (temporal lobe) | Memory deficit | X | Patient’s complain + formal NPS assessment | N/A |
9 | L_Parieto-temporal occipital | Anomia + semantic paraphasias | X | Patient’s complain + formal NPS assessment | Verbal fluency |
10 | L_Temporo occipital | Aphasia, reading difficulties | X | Patient’s complain + Evident at neurological examination | - |
11 | L_Temporo parietal | Aphasia, acalculia, apraxia, agraphia | X | Patient’s complain + formal NPS assessment | Aachener Aphasia test; Apraxia test; drawing test; acalculia test |
12 | L_ Thalamus | Memory | X | formal NPS assessment | N/A |
13a | R_Fronto-temporo occipital | Memory and attention | X | formal NPS assessment | N/A |