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Fig. 1 | Multiple Sclerosis and Demyelinating Disorders

Fig. 1

From: Myelin-derived and putative molecular mimic peptides share structural properties in aqueous and membrane-like environments

Fig. 1

Pathogen peptides mimicking MBP85-99 in membrane-like conditions. a Sequence alignment of MBP and the mimicking peptides. b NMR structure of the MBP72-107 peptide in micelles [46]. c Crystal structure of the MBP epitope bound to MHC [51]. d TFE (left) and DPC (right) titration of the EB mimic peptide. e Membrane-like conditions induced by TFE (left), DPC (middle), and SDS (right) for all four peptides. The y axis contains the relative signal at 195 nm

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