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Table 7 Factors related to the risk of developing MS in children and adolescents

From: Pediatric versus adult MS: similar or different?

Author Study population Risk factor Change in risk
Langer-Gould et al. n. 75, MS onset < 18 years BMI - Overweight x 1.58
- Moderately obese x 1.78
- Extremely obese x 3.76
Mikaeloff et al. n.90, MS onset 10 to <16 years Passive smoking x 2.49
Banwell et al. n. 49, MS onset < 16 years Remote EBV infection x 2.58
Waubant et al. n. 189, MS onset < 18 years Remote EBV infection x 3.72
Disanto et al. n. 64, MS onset < 16 years ≥1 HLA-DRB1 alleles x 3.2
McDonald et al. n. 170, MS onset < 18 years Salt intake No effect
Banwell et al. n. 63, MS onset < 16 years Vitamin D increase + 10 nmol/L 10% reduction
Monry et al. n. 110, MS onset ≤ 18 years Vitamin D increase + 10 nmol/L 30% reduction
Waubant et al. n. 189, MS onset < 18 years VCM seropositivity 73% reduction