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Table 2 Stepwise Cox proportional hazard regression model showing baseline variables associated with evidence of disease activity (NEDA-3) at 24 months after fingolimod start (n = 196)

From: Baseline characteristics associated with NEDA-3 status in fingolimod-treated patients with relapsing-remitting multiple sclerosis

Independent variables

Hazard Ratio

95% confidence intervals

P-value

Expanded Disability Status Scale (EDSS) score (each step)

1.18

1.02–1.37

0.024

Relapses (each unit)

1.61

1.10–2.35

0.014

Inserted variables that did not contribute to fit the model were as follows: sex, age, time since first symptom, multiple sclerosis severity score (MSSS), presence of gadolinium–enhancing lesions at brain MRI scan.

  1. Hazard ratios >1.0 indicates an increased risk of occurrence of any evidence of disease activity, i.e. relapses, disability worsening and/or radiological activity
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Multiple Sclerosis and Demyelinating Disorders

ISSN: 2056-6115

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