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Table 1 Baseline demographic and clinical characteristics

From: May baseline JCV status influence the MS clinical evolution during Natalizumab treatment? Evidence from a multicenter-2 years-prospective study

Characteristics

NTZ-JCV positive (n = 83)

NTZ-JCV negative (n = 101)

P-value

Age at disease onset (years), mean (SD)

29 (10)

26.5 (8.4)

0.07

Age at stratify (years), mean (SD)

39.6 (10.4)

38 (10.5)

0.29

Female (%)

53 (63.9)

74 (73.3)

0.20

Disease duration (years), mean (SD)

11.3 (8.1)

11.4 (8.6)

0.94

EDSS pre-stratify, median [IQR]; mean (SD)

3.5 (2–5); 3.1 (1.9)

3 (2–4); 3 (1.6)

0.017

Relapses year before stratify, median [IQR]; mean (SD)

1 (1–2); 1.34 (0.86)

1nn; 1.39 (0.80)

0.62

T2 lesions pre–stratify, mean (SD; IQR)

51.2 (38.5; 21–65)

51.6 (37.4; 20–70)

0.82

  1. IQR interquartile range, SD standard deviation
  2. NTZ Natalizumab, JCV John Cunningham virus