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Table 1 Patient characteristics

From: Use of rituximab and risk of re-hospitalization for children with neuromyelitis optica spectrum disorder

 

Total (n = 180)

Rituximab exposed (n = 52)

Rituximab unexposed (n = 128)

Demographics

 Female, n (%)

129 (71.7)

43 (82.7)

86 (67.2)

 Age, median (IQR)

13.0 (10.0, 15.0)

13.0 (10.0, 16.0)

12.5 (9.0, 15.0)

 Caucasiana, n (%)

72 (48.9)

14 (29.8)

58 (58.0)

 Region, n (%)

  Northeast

29 (16.1)

9 (17.3)

20 (15.6)

  Midwest

29 (16.1)

8 (15.4)

21 (16.4)

  South

98 (54.4)

30 (57.7)

68 (53.1)

  West

24 (13.3)

5 (9.6)

19 (14.8)

 Systemic lupus erythematosus, n (%)

2 (1.1)

2 (3.9)

0 (0.0)

 Sjögren syndrome, n (%)

1 (0.6)

1 (1.9)

0 (0.0)

 ICU status, n (%)

31 (17.2)

11 (21.2)

20 (15.6)

 Length of stay (days), median (IQR)

6 (3.0, 12.0)

7.0 (3.0, 17.0)

6.0 (3.0, 11.0)

Primary outcome

 Re-hospitalization in 12 months, n (%)

66 (36.7)

20 (38.5)

46 (35.9)

Secondary outcomes

 Length of re-hospitalization (days), median (IQR)

3.0 (1.0, 5.0)

2.0 (1.0, 4.0)

4.0 (2.0, 6.0)

 Time to re-hospitalization (days), median (IQR)

365 (138, 365)

365 (138, 365)

365 (137, 365)

  1. ICU intensive care unit, IQR interquartile range
  2. aRace was missing for 33 subjects. Rituximab exposure was defined as having received at least one dose of rituximab during initial hospitalization with a documented ICD-9-CM code for neuromyelitis optica (341.0)